Electromechanical Abnormalities in Patients with Paroxysmal Atrial Fibrillation
نویسندگان
چکیده
Background: The loss of effective atrial contraction is associated with an increased thromboembolic risk. Aim: To study the electromechanical coupling of the atria in patients with paroxysmal atrial fibrillation (time of occurrence of the episodes <48 hours) using pulsed-wave tissue Doppler imaging. Materials and methods: The study included 51 patients (26 men, 25 women; mean age 59.84±1.60 years) and 52 controls (26 men, 26 women; 59.50±1.46 years) without evidence to date for episodes of atrial fibrillation. We studied atrial electromechanical delay in lateral mitral annulus (P-A'MV) (ms) and tricuspid annulus (P-A'TV) (ms) as well as interatrial dyssynchrony (IAD) ((P-A'MV) (P-A'TV)) (ms). The echocardiographic study in patients was performed on the twenty fourth hour and twenty-eighth day after the restoration of sinus rhythm. In controls the echocardiographic indicators were defined once. Results: PA'MV in patients with PAF was significantly prolonged compared to controls on the twenty-fourth hour as well as twentyeighth day after the restoration of sinus rhythm (124.7±5.54 vs 106.80±2.30 ms, p=0.002; 123.2±6.12 vs 106.80±2.30 ms, p=0.006 respectively). The measurement of PA'TV showed no difference in the indicator in patients and controls (91.24±4.79 vs 87.64±1.85 ms, p=0.44; 91.70±4.92 vs 87.64±1.85 ms, p=0.38 respectively). There is an increased IAD in patients with PAF compared to controls in both measurements (31.63±3.57 vs 18.64±1.35 ms, p<0.001; 31.55±2.75 vs 18.64±1.35 ms, p<0.001). Conclusion: Our study found prolonged atrial electromechanical delay and interatrial dyssynchrony after manifestation of PAF. The short episodes of arrhythmia lead to impaired electromechanical coupling for a long period of time. In this sense AF paroxysms are a major prerequisite for relapses of the disease and significantly increase the risk of embologenic accidents.
منابع مشابه
Comparison of Prolonged Atrial Electromechanical Delays with Different Definitions in the Discrimination of Patients with Non-Valvular Paroxysmal Atrial Fibrillation
BACKGROUND AND OBJECTIVES Previous studies have evaluated atrial electromechanical delays (AEMDs) with a number of different definitions to discriminate patients with paroxysmal atrial fibrillation (PAF) from controls without PAF. However, their discriminative values for PAF have not previously been directly compared. SUBJECTS AND METHODS A total of 65 PAF patients and 130 control subjects ma...
متن کاملEvaluation of the association between stroke/transient ischemic attack and atrial electromechanical delay in patients with paroxysmal atrial fibrillation
OBJECTIVE This study aimed to evaluate the association between the history of stroke/transient ischemic attack (TIA) and inter- and intra-atrial electromechanical delay (EMD) in patients with paroxysmal atrial fibrillation (PAF). METHODS Patients diagnosed with PAF were included in this retrospective study. Patients who had a history of stroke or TIA were defined as the symptomatic group, whe...
متن کاملElectrophysiological abnormalities in patients with paroxysmal atrial fibrillation in the absence of overt structural heart disease
PURPOSE The aim of the present study was to define the atrial electrical substrate in patients with paroxysmal atrial fibrillation (AF) occurring in the absence of overt structural heart disease and to assess if electrophysiological parameters could predict AF recurrence after radiofrequency ablation in this population. METHODS AND RESULTS 45 consecutive patients (39 male, age 59 ± 10 years) ...
متن کاملClinical and Electrocardiographic comparison of patients with primary Mitral Valve Prolapse Syndrome and control group
ABSTRACT: Mitral Valve Prolapse (WVP) in one of the commonest cardiac abnormalities. Echocardiography has generally been accepted as the diagnostic modality of choice, To assess the characteristic symptoms signs and electrocardiographic abnormalities of MVP results of prospective 500 age and sex matched healthy subjects without echocardiographic MVP (control subjects). The diagnostic criteria...
متن کاملNormal dose of pilsicainide showed marked negative inotropic effects in a patient who had no underlying heart disease
We report the case of an otherwise healthy 64-year-old female who developed cardiopulmonary arrest after the administration of pilsicainide for treatment of paroxysmal atrial fibrillation. She had had an episode of paroxysmal atrial fibrillation, but no liver dysfunction, renal dysfunction, or echocardiographic abnormality before her admission. On the day of admission and the following day, 50 ...
متن کامل